VEGF-C ELISA Kit (Human) (OKBB00289)

Description of target: Vascular endothelial growth factor C is a VEGF. The human gene encoding it is VEGFC. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis, lymphangiogenesis and endothelial cell growth and survival, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D (VEGF-D). The C terminus of VEGFC has cysteine-rich repeat units characteristic of the Balbiani ring 3 protein(BR3P) of the midge Chironomus tentans1,2. The standard product used in this kit is recombinant human VEGF-C, consisting of 125 amino acids with the molecular mass of 23Kda after glycosylation.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 3 pg/ml