Recombinant Rat Eotaxin (CCL11)

Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. This factor is referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils.