Recombinant Human CTACK (CCL27)

CCL27 is a CC family chemokine which is expressed in epithelial cells and known to be up-regulated by inflammatory stimuli/wounded skin. CCL27 partakes in inflammation and wound healing – by selectively attracting and directing CLA+ T cells into the skin, and inducing the migration of keratinocyte precursors from bone marrow to the skin. High levels of this chemokine in human serum though, have been linked to the severity of various diseases, one being atopic dermatitis.