
This gene overlaps and lies on the opposite strand from FGF2 gene| and is thought to be the FGF2 antisense gene. The two genes are independently transcribed| and their expression shows an inverse relationship| suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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