
Description of target: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2a (pp2a) during mitosis. when phosphorylated at ser-67 during mitosis, specifically interacts with ppp2r2d (pr55-delta) and inhibits its activity, leading to inactivation of pp2a, an essential condition to keep cyclin-b1-cdk1 activity high during m phase. also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (abcc8), thereby preventing sulfonylurea from binding to its receptor and reducing k(atp) channel currents (by similarity);Species reactivity: Mouse;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: <0.065 ng/mL

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