XPC ELISA Kit (Mouse) (OKDD00606)

Description of target: Involved in global genome nucleotide excision repair (gg-ner) by acting as damage sensing and dna-binding factor component of the xpc complex. has only a low dna repair activity by itself which is stimulated by rad23b and rad23a. has a preference to bind dna containing a short single-stranded segment but not to damaged oligonucleotides. this feature is proposed to be related to a dynamic sensor function: xpc can rapidly screen duplex dna for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded dna-binding activity.;Species reactivity: Mouse;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: <0.061 ng/mL