CPB2 ELISA Kit (Human) : 96 Wells (OKCA00124)

Description of target: Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013];Species reactivity: Human;Application: ;Assay info: <b>Assay Methodology: </b>Quantitative Sandwich Immunoassay;Sensitivity: < 7.81 ng/ml