Zic1/2/3 Polyclonal Antibody

ZIC1 (Zic family member 1) encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of ZIC1 is seen in medulloblastoma, a childhood brain tumor. ZIC1 is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. ZIC1 encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.