MTAP ELISA Kit (Human) (OKCD00486)

Description of target: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.UniRule annotation&#xd; &lt;p>Manual validated information which has been generated by the UniProtKB automatic annotation system.&lt;/p>&#xd; &#xd; &#xd; &lt;p>&lt;a href="/manual/evidences#ECO:0000255">More…&lt;/a>&lt;/p> Manual assertion according to rulesiHAMAP-Rule:MF_031551 Publication&#xd; &lt;p>Manually curated information for which there is published experimental evidence.&lt;/p>&#xd; &#xd; &#xd; &lt;p>&lt;a href="/manual/evidences#ECO:0000269">More…&lt;/a>&lt;/p> Manual assertion based on experiment iniRef.8"Purification and characterization of 5'-deoxy-5'-methylthioadenosine phosphorylase from human placenta."_x005F_x005F_x000D_Della Ragione F., Carteni-Farina M., Gragnaniello V., Schettino M.I., Zappia V._x005F_x005F_x000D_J. Biol. Chem. 261:12324-12329(1986) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, SUBUNIT. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.063 ng/mL