MEK-1(Phospho Thr386) Polyclonal Antibody

The protein encoded by this gene is a member of the dual specificity protein kinase family| which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases| also known as extracellular signal-regulated kinases (ERKs)| act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway| this kinase is involved in many cellular processes such as proliferation| differentiation| transcription regulation and development.