Kv2.1/KCNB1 Polyclonal Antibody

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release| heart rate| insulin secretion| neuronal excitability| epithelial electrolyte transport| smooth muscle contraction| and cell volume. Four sequence-related potassium channel genes - shaker| shaw| shab| and shal - have been identified in Drosophila| and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel| voltage-gated| shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.