IP3 Receptor(Phospho Tyr353) Rabbit Polyclonal Antibody

This gene encodes an intracellular receptor for inositol 1|4|5-trisphosphate. Upon stimulation by inositol 1|4|5-trisphosphate| this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15| a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.