IL11 Chemi-Luminescent ELISA Kit (Mouse) (OKCD03616)

Description of target: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production . Also promotes the proliferation of hepatocytes in response to liver damage . Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation, also in the context of various cancers . Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3 .;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.37 pg/mL