IL-8RA Polyclonal Antibody

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity| and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene| IL8RB| a gene encoding another high affinity IL8 receptor| as well as IL8RBP| a pseudogene of IL8RB| form a gene cluster in a region mapped to chromosome 2q33-q36.