IL-11R Alpha Polyclonal Antibody

Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. IL11RA encodes the Interleukin-11 receptor subunit alpha, which is a member of the hematopoietic cytokine receptor family. Interleukin-11 receptor subunit alpha is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.