Histone H1 (Di Methyl Lys25) Polyclonal Antibody

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST1H1A is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from HIST1H1A lack polyA tails but instead contain a palindromic termination element. HIST1H1A is found in the large histone gene cluster on chromosome 6.