Gemtuzumab ozogamicin

Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a cytotoxic derivative of Calicheamicin, and a monoclonal antibody targeting CD33 antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia[1].