eIF2B Gamma Polyclonal Antibody

Eukaryotic translation initiation factor 2B subunit gamma encoded by EIF2B3 is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in EIF2B3 have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for EIF2B3.