
Description of target: Ectodysplasin A (EDA) is a protein that in humans is encoded by the EDA gene. It is mapped to Xq22. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. ;Species reactivity: Rat;Application: ELISA;Assay info: ;Sensitivity: <50pg/ml
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