DCAMKL3 Polyclonal Antibody

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. DCAMKL3 (doublecortin-like and CAM kinase-like 3), also known as DCLK3 or DCDC3C, is a 648 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain. One of several members of the Ser/Thr protein kinase family, DCAMKL3 functions to catalyze the ATP-dependent attachment of a phospho residue to target proteins, an event that may play a role in various cellular processes.