CCL5 ELISA Kit (Guinea Pig) (OKCD00217)

Description of target: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.By similarity&#xd; &lt;p>Manually curated information which has been propagated from a related experimentally characterized protein.&lt;/p>&#xd; &#xd; &#xd; &lt;p>&lt;a href="/manual/evidences#ECO:0000250">More…&lt;/a>&lt;/p> Manual assertion inferred from sequence similarity toiUniProtKB:P13501&nbsp;(CCL5_HUMAN) ;Species reactivity: Guinea Pig;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.055 ng/mL