CAPS1 Rabbit Polyclonal Antibody

This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming| which involves the essential synthesis of phosphatidylinositol 4|5-bisphosphate (PtdIns(4|5)P2). Alternative splicing has been observed at this locus and three variants| encoding distinct isoforms| are described.