BMPR1B ELISA Kit (Mouse) (OKCA01634)

Description of target: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1. Receptor for GDF5 (PubMed:26105076, PubMed:19229295). Positively regulates chondrocyte differentiation through GDF5 interaction (PubMed:24098149).;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sanadwich ELISA;Sensitivity: 0.039 ng/mL