Apixaban-d3

Apixaban-d3 (BMS-562247-01-d3)is the deuterium labeledApixaban(HY-50667)[1]. Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively[2]. Apixaban is in development for the prevention and treatment of various thromboembolic diseases[3].