Anti-Human FGF-17 Antibody

Fibroblast growth factors (FGFs) play multiple biological functions including angiogenesis, mitogenesis, cellular differentiation and wound repairing. All members of the FGF family have a conserved approximately 120 amino acid core with 30-70% identity. Among FGF family members, FGF17 is most similar to FGF8 (60% sequence identity) and FGF18 (50% sequence identity). The mRNA of FGF17 was found in midgestation of embryo and multiple adult tissues, and is preferentially expressed in specific sites, such as embryonic brain, developing skeleton and arteries. Human FGF17 shares 98.6% amino acid (aa) sequence identity with mouse FGF17. Rat FGF17 shares 100% aa sequence identity with mouse FGF17.