
The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.|PTM:eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).|Belongs to the eIF-5A family.|tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells.|

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